The histogenetic aspects of plant development depend on regulation of cell division plane, timing and frequency to produce cell units of correct size and shape for mature function. Differences among the dermal, ground and vascular tissue systems arise during development, largely through regulation of these aspects of cell cycling in relation to overall tissue expansion. Using a cyclin1At::GUS reporter construct, we demonstrate quantitative differences in cell cycling frequency among tissue systems and among primary, secondary, and tertiary veins; these differences are superimposed upon the more general longitudinal gradient of cell division frequency in developing leaves of Arabidopsis thaliana. Patterns of cell cycling frequency coincide almost exactly with those of the earliest known molecular marker of procambial identity, the HD-ZIP class III homeobox gene ATHB-8, suggesting that ATHB-8 may play a role in regulating the early events of procambial development, including procambium-specific patterns of cell cycling.

Key words: Arabidopsis thaliana homeobox gene-8, Arabidopsis, cell cycle, leaf development, procambium, vein pattern