In the tribe Antirrhineae there has been a single evolutionary transition from the ancestral condition of four mature stamens per flower (found in Antirrhinum majus) to the derived condition of two mature stamens (found in Mohavea). Wild-type A. majus flowers initiate five stamens, however the adaxial stamen aborts early in development. Molecular genetic work with A. majus has shown that the floral symmetry genes CYCLOIDEA (CYC) and DICHOTOMA (DICH) determine adaxial flower identity and that CYC is necessary for stamen abortion. Mohavea is a traditionally recognized genus of two species, M. confertiflora and M. breviflora, embedded within a tetraploid clade of North American Antirrhinum. The flowers of Mohavea develop similarly to those of A. majus except stamen abortion is seen in the two lateral, in addition to the adaxial stamen. Using mRNA in situ hybridization, we show that the M. confertiflora homologs of CYC (McCYC1 and McCYC2) and DICH (McDICH1) are expressed in both dorsal and lateral stamen primordia during M. confertiflora flower development. The evolutionary loss of lateral stamens has likely been caused by changes in the spatial regulation of these loci. Expression data suggest the possibility that McDICH2 is under relaxed purifying selection relative to McDICH1. Patterns of molecular evolution across tetraploid North American Antirrhinum, including Mohavea, do not support this hypothesis and suggest instead that both CYC and both DICH loci are under purifying selection following their origins via genome duplication.

Key words: Antirrhineae, CYCLOIDEA, DICHOTOMA, tetraploid evolution