BACHVAROFF, T. R.1*, E. M. HERMAN2, and C. F. DELWICHE1. 1Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742 USA; 2Soybean Genomic Improvement Laboratory, USDA/ARS, Beltsville, MD 20705 USA. - Dinoflagellate genomics: results from an EST approach.
Dinoflagellates are enigmatic protists with odd nuclear features,
interesting plastid gene arrangements and a proclivity for
endosymbiotic relationships. Relatively little molecular work has been
done on Dinoflagellates, and only a handful of genes have been
characterized in these organisms. We have begun an Expressed Sequenced
Tag (EST) project with the aim of collecting plastid targeted but
nuclear encoded genes from peridinin-containing dinoflagellates. This
provides an opportunity to understand the integration of endosymbiont
genes into the host cell. Our sequencing effort has produced about one
thousand unique ESTs from a Gonyaulax polyedra cDNA library
obtained from David Morse. Of the 1535 total ESTs (72% > 400 b.p.) 466
sequences were identifiable by BLAST with a bitscore above 50. The
most abundant transcript is the peridinin-chlorophyll binding protein,
which constituted 3% of the clones. More recently we began sequencing
from an Amphidinium carterae cDNA library made in our
laboratory. This provides insight into expression patterns and is a
resource for other workers in the field. Several clearly identifiable
plastid genes have been found and preliminary analysis confirms the
chromophyte, and therefore, tertiary origin of the peridinin plastid.
Key words: chromophyte algae, Dinoflagellates, EST, plastid evolution